Necrostatin-1
RIP1激酶抑制剂；5-(吲哚-3-甲基)-3-甲基-2-硫海因
Necrostatin-1
RIP1激酶抑制剂；5-(吲哚-3-甲基)-3-甲基-2-硫海因
Necrostatin-1
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产品编号： CNR388550
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CAS号： 4311-88-0
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分子式：C13H13N3Os
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分子量：259.33
英文别名：
5-(Indol-3-ylmethyl)-3-methyl-2-thiohydantoin
参考文献：
Foresti, R., et al: J. Biol. Chem., 272, 18411 (1997); Cardenas, A., et al.: J. Neurochem., 74, 2041 (2000); Degterev, et al.: Nat. Chem. Biol., 1, 112 (2005); Hitomi, J., et al.: Cell, 135, 1311 (2008);
Necroptosis is a regulated caspase-independent cell death mechanism that results in morphological features resembling necrosis. Necrostatin-1 is an inhibitor of RIP1 kinase that prevents the death of TNF-α-treated FADD-deficient Jurkat cells. Necrostatin-
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