LRRK2-IN-1
帕金森激酶抑制剂；5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]甲酰]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-b][1,4]苯并二氮杂卓-6-酮
LRRK2-IN-1
帕金森激酶抑制剂；5,11-二氢-2-[[2-甲氧基-4-[[4-(4-甲基-1-哌嗪基)-1-哌啶基]甲酰]苯基]氨基]-5,11-二甲基-6H-嘧啶并[4,5-b][1,4]苯并二氮杂卓-6-酮
LRRK2-IN-1
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产品编号： CLR473450
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CAS号： 1234480-84-2
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分子式：C31H38N8O3
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分子量：570.09
英文别名：
5,11-Dihydro-2-[[2-methoxy-4-[[4-(4-methyl-1-piperazinyl)-1-piperidinyl]carbonyl]phenyl]amino]-5,11-dimethyl-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
SMILES：
ClCOC([C@]1(CC[C@]2([H])[C@]1(C)C[C@@H]([C@]1([H])[C@@]3(C)C=CC(C=C3CC[C@@]21[H])=O)O)OC(=O)OCC)=O
参考文献：
Deng, X.M., et al.: Nature. Chem. Biol., 7, 203 (2011); Choi, H.G., et al.: ACS. Medn. Chem. Letters., 3, 658 (2012);
LRRK2-IN-1 is a benzodiazepine based derivative and is known as a selective inhibitor of the Parkinson's disease kinase LRRK2.
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