LM-22A4
N,N’,N’’-三(β-羟基乙基)苯三甲酰胺
LM-22A4
N,N’,N’’-三(β-羟基乙基)苯三甲酰胺
LM-22A4
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产品编号： CLR469290
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CAS号： 37988-18-4
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分子式：C15H21N3O6
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分子量：339.34
英文别名：
N,N’,N’’-Tris(β-hydroxyethyl)trimesamide
SMILES：
CC(CCCCN1C(=O)N(C)C2N=CN(C)C=2C1=O)O
参考文献：
Massa, S.M. et al.: J. Clin. Invest., 120, 1774 (2010); Schmid, D.A. et al.: J. Neurosci., 32, 1803 (2012);
LM 22A4 is a potent tropomyosin-related kinase B (TrkB) agonist. LM 22A4 has been show to induce activation of Trk, Akt and ERK in mouse hippocampus and striatum and reverse deficits in motor task learning in mice following traumatic brain injury. LM 22A4 also restored respiratory function in a rat model of Rett syndrome.
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