Linsitinib-d3
IGF-IR/抑制剂内标物
Linsitinib-d3
IGF-IR/抑制剂内标物
Linsitinib-d3
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产品编号： CLR469022
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分子式：C26H20D3N5O
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分子量：424.51
英文别名：
OSI-906-d3
参考文献：
Mulvihill, M.M.J. et al.: Fut. Med. Chem., 1, 1153 (2009); Flanigan, S.A. et al.: Clin. Cancer Res., 16, 5436 (2010); McKinley, E.T. et al.: Clin. Cancer Res., 17, 3332 (2011);
Labelled Linsitinib (L469020). Linsitinib is a small-molecule dual insulin-like growth factor-1 receptor (IGF-IR) and insulin receptor (IR) kinase inhibitor. IGF-I receptor (IGF-IR) has been implicated in the promotion of tumorigenesis, metastasis and resistance to cancer therapies and thus Linsitinib may be a useful anticancer agent.
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