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Linsitinib
IGF-IR/抑制剂
Linsitinib
  • 产品编号: CLR469020

  • CAS号: 867160-71-2

  • 分子式:C26H23N5O

  • 分子量:421.49

英文别名:
OSI-906
参考文献:
Mulvihill, M.M.J. et al.: Fut. Med. Chem., 1, 1153 (2009); Flanigan, S.A. et al.: Clin. Cancer Res., 16, 5436 (2010); McKinley, E.T. et al.: Clin. Cancer Res., 17, 3332 (2011);
Linsitinib is a small-molecule dual insulin-like growth factor-1 receptor (IGF-IR) and insulin receptor (IR) kinase inhibitor. IGF-I receptor (IGF-IR) has been implicated in the promotion of tumorigenesis, metastasis and resistance to cancer therapies and thus Linsitinib may be a useful anticancer agent.
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