Letaxaban-d5
Letaxaban-d5
FXa抑制剂内标物
Letaxaban-d5
FXa抑制剂内标物
Letaxaban-d5
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产品编号: CLR329852
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CAS号: 1346617-07-9
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分子式:C22H21D5ClN3O5S
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分子量:485.01
英文别名:
1-[1-[(2S)-3-[(6-chloro-2-naphthalenyl)sulfonyl]-2-hydroxy-1-oxopropyl]-4-(piperidinyl-d5)]tetrahydro-2(1H)-pyrimidinone; TAK 442-d5; 1-[(2S)-3-[(6-Chloro-2-naphthalenyl)sulfonyl]-2-hydroxy-1-oxopropyl]-4-(tetrahydro-2-oxo-1(2H)-pyrimidinyl)piperidine-d5;
参考文献:
Zufferey, P.J. et al.: Thromb. Haemost., 104, 1083 (2010); Kawamura, M. et al.: J. Cardio. Pharmacol., 56, 156 (2010); Fujimoto, T. et al.: J. Med. Chem., 53, 3517 (2010);
A labelled potent and selective orally active factor Xa (FXa) inhibitor; anticoagulant. Effective in preventing venous thromboembolism in patient undergoing orthopedic surgery.
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