(S)-劳丹素
(S)-劳丹素
(R)-乐卡地平盐酸盐
(S)-Laudanosine
(R)-乐卡地平盐酸盐
(S)-Laudanosine
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产品编号: CLR178525
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CAS号: 2688-77-9
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分子式:C36H42ClN3O6
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分子量:648.19
英文别名:
(4R)-1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride;
SMILES:
COC1C=CC(C[C@@H]2N(C)CCC3=CC(=C(C=C23)OC)OC)=CC=1OC
参考文献:
Canfell, P., et al.: Drug Metab. Dispos., 14, 703 (1986), Anselmi, E., et al.: J. Pharm. Pharmacol., 44, 337 (1992), Bohrer, H., et al.: Pharmacol. Toxicol., 73, 137 (1993),
Laudanosine is a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
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