甲苯磺酸拉帕替尼-d7
甲苯磺酸拉帕替尼-d7；拉帕替尼-d7 甲苯磺酸盐
Lapatinib-d7 Ditosylate
甲苯磺酸拉帕替尼-d7；拉帕替尼-d7 甲苯磺酸盐
Lapatinib-d7 Ditosylate
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产品编号： CLR175803
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CAS号： 1009307-24-7
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分子式：C43H35D7ClFN4O10S3
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分子量：932.5
英文别名：
N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[5-[[[2-(methylsulfonyl)ethyl-d7]amino]methyl]-2-furanyl]-4-quinazolinamine Bis(4-methylbenzenesulfonate) Ditosylate; GW-572016F-d7 Ditosylate; Tykerb-d7 Ditosylate;
SMILES：
FC1=CC=CC(COC2C=CC(NC3=NC=NC4C=CC(C5=CC=C(CNC(C(S(C([2H])([2H])[2H])(=O)=O)([2H])[2H])([2H])[2H])O5)=CC3=4)=CC=2Cl)=C1.CC1C=CC(S(=O)(O)=O)=CC=1
参考文献：
Kim, T.E., et al.: Drugs, 6, 886 (2003), Wood, E.R., et al.: Cancer Res., 64, 6652 (2004), Spector, N.L., et al.: J. Clin. Oncol., 23, 2502 (2005),
Labelled Lapatinib (L175800). Reversible dual inhibitor of ErbB1 and ErbB2 tyrosine kinases. Antineoplastic.
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