L-659989
血小板活化因子(PAF)受体拮抗剂；反式-(±)-四氢-2-[3-甲氧基-5-(甲磺酰)-4-丙氧苯基]-5-(3,4,5-三甲氧基苯基)呋喃
L-659989
血小板活化因子(PAF)受体拮抗剂；反式-(±)-四氢-2-[3-甲氧基-5-(甲磺酰)-4-丙氧苯基]-5-(3,4,5-三甲氧基苯基)呋喃
L-659989
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产品编号： CLR009500
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CAS号： 113787-28-3
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分子式：C24H32O8S
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分子量：480.57
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EINECES：200-362-1
英文别名：
trans-(±)-Tetrahydro-2-[3-methoxy-5-(methylsulfonyl)-4-propoxyphenyl]-5-(3,4,5-trimethoxyphenyl)furan
SMILES：
O=C1N(C2N=CN(C)C=2C(=O)N1C)C
参考文献：
Hussaini, I.M. et al.: Acta Pharmacol. Sin., 21, 897 (2000); Gomez-M. et al.: Biochim. Biophys. Acta, 1438, 247 (1999); Ioculano, M. et al.: J. Cardio. Pharmacol., 23, 7 (1994);
L-659989 is a platelet-activating factor (PAF) receptor antagonist. L-659989 is also a potent inhibitor of phospholipase D activity at higher concentrations. L-659989 showed cardioprotective effects as it inhibited heart injury from ischemia and reperfusion in rats.
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