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KRN-7000
蛋白酶C活性调节剂
KRN7000
  • 产品编号: CKR660000

  • CAS号: 158021-47-7

  • 分子式:C50H99NO9

  • 分子量:858.32

英文别名:
N-[(1S,2S,3R)-1-[(α-D-Galactopyranosyloxy)methyl]-2,3-dihydroxyheptadecyl]hexacosanamide
熔点:
125-130°C
可溶性:
Pyridine, 0.2mg per ml PBS plus 0.5% Tween-20 and sonicate for 2hrs
性状:
White to Off-White Solid
SMILES:
OC[C@@H]1[C@@H](O)[C@H](O)[C@H](O)[C@H]2NC(C(=O)N12)=O
储存条件:
-20°C Freezer
参考文献:
Morita, M., et al.: J. Med. Chem., 38, 2176 (1995), Sakai, T., et al.: J. Med. Chem., 42, 1836 (1999),
Galactosylceramides play an important roles in promoting the regulation of nerve cells, regulating protein kinase C activities and modulating the function of the hormone receptor. It has shown to have significant immunostimulatory and anti-umor activity in mice with liver metastasis of the Colon26 adenocarcinoma.
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