KAAD-环杷明
KAAD-环巴胺；KAAD-环杷明；3-酮基-N-氨乙基-N’-氨基己酰二氢肉桂酰环巴胺；3-酮基-N-氨乙基-N’-氨基己酰二氢肉桂酰环杷明>80%
KAAD-Cyclopamine
KAAD-环巴胺；KAAD-环杷明；3-酮基-N-氨乙基-N’-氨基己酰二氢肉桂酰环巴胺；3-酮基-N-氨乙基-N’-氨基己酰二氢肉桂酰环杷明>80%
KAAD-Cyclopamine
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产品编号： CKR171000
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CAS号： 306387-90-6
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分子式：C44H63N3O4
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分子量：697.99
英文别名：
KAAD-Cyclopamine;
熔点：
N/A
可溶性：
Chloroform, Methanol
性状：
Pale Yellow Solid
储存条件：
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
参考文献：
Taipale, J., et al.: Nature, 406, 1005 (2000); Perron, M., et al.: Development, 130, 1565 (2003);
Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of ß-Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity.
KAAD-Cyclopamine compound is unstable in solution.
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