JNJ-7706621
CDKs抑制剂
JNJ-7706621
CDKs抑制剂
JNJ-7706621
-
产品编号： CJR211310
-
CAS号： 443797-96-4
-
分子式：C15H12F2N6O3S
-
分子量：394.36
英文别名：
N3-[4-(Aminosulfonyl)phenyl]-1-(2,6-difluorobenzoyl)-1H-1,2,4-triazole-3,5-diamine
SMILES：
CCCCCC1COCCC1OC(=O)C
参考文献：
Matsuhashi, A. et al.: Curr. Cancer Drug Tar., 12, 625 (2012); Emanue,l S. et al.: Cancer Res., 65, 9038 (2005); Seamon, J.A. et al.: Mol. Cancer Ther., 5, 2459 (2006);
JNJ-770662 is a broad spectrum inhibitor of cyclin-dependent kinases and aurora kinases including CDK1/Cyclin B, CDK2/Cyclin A, CDK2/Cyclin E, Aurora-A and Aurora-B. JNJ-770662 has been shown to induce growth suppression and mitotic defects, these results suggest that JNJ-7706621 could be useful for cell cycle analysis and therapy of various cancers, including Ewing's sarcoma.
搜索质检报告(COA)
搜索MSDS
