IWP-2
IWP-2
N-(6-甲基-2-苯并噻唑基)-2-[(3,4,6,7-四氢-4-酮代-3-苯己噻吩并[3,2-d]嘧啶-2-基)硫]乙酰胺
IWP-2
N-(6-甲基-2-苯并噻唑基)-2-[(3,4,6,7-四氢-4-酮代-3-苯己噻吩并[3,2-d]嘧啶-2-基)硫]乙酰胺
IWP-2
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产品编号: CIR941600
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CAS号: 686770-61-6
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分子式:C22H18N4O2S3
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分子量:466.6
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EINECES:202-599-6
英文别名:
N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]acetamide
SMILES:
OC(CC(C(=O)O)=C)=O
参考文献:
Poss, K., et al.: Dev. Biol., 222, 347 (2000), Tanaka, K., et al.: Eur. J. Biochem., 267, 4300 (2000), Clevers, H., et al.: Cell, 2006, 127, 469 (2006),
IWP-2 is an inactivator of Porcn function; inhibitor of Wnt production. IWP-2 is useful in the treatment diseases and conditions such as cancer, degenerative diseases, type II diabetes and osteopetrosis.
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