异秋水仙碱
异秋水仙碱；异地美可辛
Isodemecolcine
异秋水仙碱；异地美可辛
Isodemecolcine
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产品编号： CIR814125
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CAS号： 4702-33-4
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分子式：C21H25NO5
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分子量：371.43
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EINECES：200-438-4
英文别名：
Isocolchicine
可溶性：
Chloroform, Dichlormethane, DMSO, Ethanol, Ethyl Acetate, Methanol
性状：
Yellow Solid
SMILES：
C(NNC(C1C=C(C)ON=1)=O)C1C=CC=CC=1
参考文献：
Lunduena, R.F., et al.: Curr. Opin. Cell Biol., 4, 53 (1992), Ceccatelli, S., et al.: Neuroreport, 8, 3779 (1997), Want, T.H., et al.: J. Biol. Chem., 273, 4928 (1998), Andreu, J.M., et al.: Biochemistry, 37, 8356 (1998), Jordan, A., et al.: Med. Res. Rev
An antimitotic agent that disrupts microtubles by binding to tubulin and preventing its polymerization. Stimulates the intrinsic GTPase activity of tubulin. Induces apoptosis in several normal and tumor cell lines and activates the JNK/SAPK signaling pathway.
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