异巴比妥酸
异巴比妥酸
异巴比妥酸;2,4,5-三羟基嘧啶
Isobarbituric Acid
异巴比妥酸;2,4,5-三羟基嘧啶
Isobarbituric Acid
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产品编号: CIR780030
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CAS号: 496-76-4
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分子式:C4H4N2O3
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分子量:128.09
英文别名:
2,4,5-Trihydroxypyrimidine; Dihydro-2,4,5(3H)-pyrimidinetrione; 5-Hydroxyuracil; NSC 95958;
SMILES:
OCC1C2=C(C)C3(CC3)C(O)(C)C(=O)C2=CC=1C
参考文献:
Varatharasa T. et al.: Chem. Comm., 3, 400 (2005); Jaruga, P. et al.: Nucleic Acid Res., 24, 1389 (1996); Rodriguez, H. et al.: Adv. Exp. Med. Biol., 534, 129 (2003);
A 5-hydroxy derivative of the nucleobase Uracil (U801000) and an isomer of Barbituric Acid (B118650). Studies show that it can form stable base pairs with all four bases in a DNA duplex. It has been used as oxidative DNA damage biomarker in tissue engineered skin
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