艾沙康唑-d4
艾沙康唑-d4
Isavuconazole-d4
艾沙康唑-d4
Isavuconazole-d4
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产品编号： CIR777832
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CAS号： 1346598-58-0
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分子式：C22H13D4F2N5Os
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分子量：441.49
英文别名：
4-[2-[(1R,2R)-2-(2,5-Difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]-4-thiazolyl]benzonitrile-d4; 2R,3R)-3-[4-(4-Cyanophenyl)thiazol-2-yl]-2-(2,5-
difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol-d4;
参考文献：
Ohwada, J., et al.: Bioorg. Med. Chem. Lett., 13, 191 (2003), Guinea, J., et al.: Antimicrob. Agents Chemother., 52, 1396 (2008)
Labelled Isavuconazole (I777832). It is a new triazole currently undergoing phase III clinical trials. This compound has shown in vitro activity against a large number of clinical important yeasts and molds including Aspergillus spp., Fusarium spp., Scedosporium spp., Candida spp., the Zygomycetes and Cryptococcus spp.
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