IDRA-21
AMPA受体抑制剂
IDRA-21
AMPA受体抑制剂
IDRA-21
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产品编号： CIR232500
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CAS号： 22503-72-6
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分子式：C8H9ClN2O2S
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分子量：232.69
英文别名：
7-Chloro-3,4-dihydro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-Dioxide
参考文献：
Zivkovic, et al.: J. Pharmacol. Exp. Ther., 272, 300 (1995), Dingledine, R., et al.: Pharmacol. Rev., 51, 7 (1999), Sun, Y., et al.: Nature, 417, 245 (2002), Thomsen, R., et al.: J. Med. Chem., 49, 3315 (2006),
IDRA-21 inhibits AMPA receptor desensitization and enhances cognition by a related mechanism. IDRA-21 is more able to cross the blood-brain barrier than Cyclothiazide (C988960).
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