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2,2’-(羟基亚硝基肼基)双乙胺
2,2’-(羟基亚硝基肼基)双乙胺
2,2’-(Hydroxynitrosohydrazino)bis-Ethamine
  • 产品编号: CHR948700

  • CAS号: 146724-94-9

  • 分子式:C4H13N5O2

  • 分子量:163.18

英文别名:
NOC 18, DETA NONOate,
可溶性:
Water
性状:
White Powder
SMILES:
OC(COC1C2C(=CC=CC=2)C=CC=1)CN1C(=O)CCC1=O
参考文献:
Hrabie, J.A. et al.: J. Org. Chem., 58, 1472 (1993); Seccia, M. et al.: Biochem. Biophys. Res. Comm., 220, 306 (1996); Shibuta, S. et al.: Neurosci. Lett., 187, 103 (1995)
A stable NO-amine complex which can release NO spontaneously under physiological conditions. The half life of NO release in 0.1 M PBS at (pH7.4) at 37˚C for 0.1mM NOC 5 is 21 hours. Other applications include the induction of dose dependent apoptosis in macrophages, and inhibition of lipoprotein oxidation induced by Cu2+ in vitro.
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