(2R,3S)-β-羟基亮氨酸
洛伐他汀代谢物；(S,S)-3-羟基洛伐他汀
(2R,3S)-β-Hydroxyleucine
洛伐他汀代谢物；(S,S)-3-羟基洛伐他汀
(2R,3S)-β-Hydroxyleucine
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产品编号： CHR943740
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CAS号： 87421-23-6
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分子式：C24H36O6
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分子量：420.54
英文别名：
[1S-[1α(2R*,3R*),3α,7β,8β(2S*,4S*),8aβ]]-3-Hydroxy-2-methylbutanoic Acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-
2-yl)ethyl]-1-naphthalenyl Ester;
SMILES：
NC(C(O)C(C)C)C(O)=O
参考文献：
Hovhannisyan, N. et al.: Amino Acids, 37, 531 (2009); Chitchyan, M.B. et al.: Hayas. Kensab. Hand., 59, 248 (2007);
(2R,3S)-β-Hydroxyleucine is a nonprotein amino acid. (2R,3S)-β-Hydroxyleucineis an inhibitor of serine protease. In particular, (2R,3S)-β-Hydroxyleucine was effective in inhibiting trypsin and proteinase K of the serine proteases group. (2R,3S)-β-Hydroxyleucine was not able to inhibit the growth of gram-positive and gram-negative bacteria and yeasts unlike its (2S,3R)-isomer.
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