β-羟基异戊酸
亮氨酸代谢物；β-羟基异戊酸；3-羟基异戊酸
β-Hydroxyisovaleric Acid
亮氨酸代谢物；β-羟基异戊酸；3-羟基异戊酸
β-Hydroxyisovaleric Acid
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产品编号： CHR943605
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CAS号： 625-08-1
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分子式：C5H10O3
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分子量：118.13
英文别名：
3-Hydroxy-3-methylbutanoic Acid; 3-Hydroxy-3-methylbutyric Acid; 3-Hydroxyisovaleric Acid; β-Hydroxy-β-methylbutyric Acid;
SMILES：
N1C2C(=CC=CC=2O)C=C1
参考文献：
Nissen, S. et al.: J. Appl. Physiol., 81, 2095 (1996); Wilson, G.J. et al.: Nutrit. Metab., 5, 1 (2008); Mock, D.M. et al.: Am. J. Clin. Nutrit., 76, 1061 (2002);
β-Hydroxyisovaleric Acid is a metabolite of the essential amino acid Leucine and is synthesized in the human body. Studies suggest that β-Hydroxyisovaleric Acid may have an effect on increasing muscle weight and strength. The presence of elevated β-Hydroxyisovaleric Acid is a sensitive marker of biotin deficiency and may indicate the presence of a genetic disorder such as biotinidase deficiency or holocarboxylase synthetase deficiency.
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