羟基法舒地尔盐酸盐
法舒地尔代谢物；羟基法舒地尔盐酸盐
Hydroxy Fasudil Hydrochloride
法舒地尔代谢物；羟基法舒地尔盐酸盐
Hydroxy Fasudil Hydrochloride
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产品编号： CHR942380
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CAS号： 155558-32-0
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分子式：C14H18ClN3O3S
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分子量：343.83
英文别名：
1-(1-Hydroxy-5-isoquinolinesulfonyl)homopiperazine Hydrochloride;
5-[(Hexahydro-1H-1,4-diazepin-1-yl)sulfonyl]-1(2H)-isoquinolinone; HA1100 Hydrochloride;
熔点：
>250 (dec.)
可溶性：
Aqueous Acid, Methanol (Sparingly)
性状：
Off-White Solid
SMILES：
C(OCCO)(=O)C1C=CC(C(OC)=O)=CC=1
储存条件：
-20°C Freezer
参考文献：
Shimokawa, H., et al.: Cardiovasc. Res., 43, 1029 (1999), Takemoto, M., et al.: Circulation, 106, 57 (2002), Ito, K., et al.: J. Physiol., 546, 823 (2003),
A metabolite of Fasudil. A cell-permeable, hydroxylated metabolite of HA 1077 that displays anti-anginal properties. Reported to inhibit the Rho kinase-mediated (ROCK) contraction both in vitro and in vivo.
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