4-羟基雌酮 1-N7-鸟嘌呤
4-羟基雌酮 1-N7-鸟嘌呤
4-Hydroxy Estrone 1-N7-Guanine
4-羟基雌酮 1-N7-鸟嘌呤
4-Hydroxy Estrone 1-N7-Guanine
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产品编号： CHR942120
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CAS号： 178971-92-1
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分子式：C23H25N5O4
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分子量：435.48
英文别名：
4-OH-E1-1-N7Gua
SMILES：
OCCOC1C2=C(N=C(N)N=1)N(C=N2)C3OC(CO)C(O)C3
参考文献：
Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),
4-Hydroxy Estrone 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.
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