4-羟基雌二醇 1-N3-腺嘌呤
4-羟基雌二醇 1-N3-腺嘌呤
4-Hydroxy Estradiol 1-N3-Adenine
4-羟基雌二醇 1-N3-腺嘌呤
4-Hydroxy Estradiol 1-N3-Adenine
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产品编号： CHR942100
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CAS号： 428506-88-1
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分子式：C23H27N5O3
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分子量：421.49
英文别名：
4-OH-E2-1-N3Ade
参考文献：
Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),
4-Hydroxy Estradiol 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.
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