2-羟基异喹啉-1,3(2H,4H)-二酮
2-羟基异喹啉-1,3(2H,4H)-二酮；2-羟基-1,3(2H,4H)-异喹啉二酮
2-Hydroxyisoquinoline-1,3(2H,4H)-dione
2-羟基异喹啉-1,3(2H,4H)-二酮；2-羟基-1,3(2H,4H)-异喹啉二酮
2-Hydroxyisoquinoline-1,3(2H,4H)-dione
-
产品编号： CHR939800
-
CAS号： 6890-08-0
-
分子式：C9H7NO3
-
分子量：177.16
英文别名：
2-Hydroxy-1,3(2H,4H)-isoquinolinedione;
熔点：
197-200°C
可溶性：
DMSO
性状：
Brown Solid
储存条件：
Refrigerator
参考文献：
Greenwald, J., et al.: Biochemistry, 38, 8892 (1999), Tramontano, E., et al.: Antiviral Res., 65, 117 (2005), Schultz, S., et al.: Virus Res., 134, 86 (2008), Williams, P., et al.: Bioorg. Med. Chem. Lett., 22, 6754 (2010),
2-Hydroxyisoquinoline-1,3(2H,4H)-dione was recently discovered as a scaffold for the inhibition of HIV-1 integrase and the RNase H function of HIV-1 reverse transcriptase. It was investigated its interaction with Mg2+ and Mn2+ using different spectroscopic techniques and report that 2-hydroxyisoquinoline-1,3(2H,4H)-dione forms a 1:1 complex with Mg2+ but a 1:2 complex with Mn2+. Antiviral agent.
搜索质检报告(COA)
搜索MSDS
