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3α-羟基去氧蒿甲醚
蒿甲醚代谢物;青蒿素衍生物;3α-羟基去氧蒿甲醚;3α-羟基脱氧蒿甲醚
3α-Hydroxydesoxy Artemether
  • 产品编号: CHR939050

  • CAS号: 174097-70-2

  • 分子式:C16H26O5

  • 分子量:298.37

英文别名:
(2S,3R,3aS,6R,6aS,8R,9S,10aR,10bR)-Decahydro-2-methoxy-3,6,9-trimethyl-10aH-9,10b-epoxypyrano[4,3,2-jk][2]benzoxepin-8-ol; 3α-Hydroxydeoxyartemether;[2S-(2α,3α,3aβ,6β,6aβ,8β,9β,10aα,10bβ)]-Decahydro-2-methoxy-3,6,9-trimethyl-10aH-9,10b-Epoxypyrano[4,3,2-j
SMILES:
OC1C=CC2N=C(C3=CC=CC=C3SC=2C=1)N1CCNCC1
参考文献:
Smith, S.L. et al.: Neurotoxicology, 19, 557 (1998); Abourashed, E.A. et al.: J. Natur. Prod., 59, 251 (1996);
A metabolite of Artemether (A777400) and derivative of the antimalarial drug Artemisinin (A777500). Studies suggest that it may display neurotoxicity in animals due to its interaction with iron.
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