(Z)-4-羟基-N-去甲他莫昔芬
他莫昔芬代谢物；(Z)-4-羟基-N-去甲他莫昔芬(含10%E-异构体)
(Z)-4-Hydroxy-N-desmethyl Tamoxifen
他莫昔芬代谢物；(Z)-4-羟基-N-去甲他莫昔芬(含10%E-异构体)
(Z)-4-Hydroxy-N-desmethyl Tamoxifen
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产品编号： CHR938500
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CAS号： 112093-28-4
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分子式：C25H27NO2
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分子量：373.49
英文别名：
4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol;
熔点：
127-129°C
可溶性：
Chloroform, Methanol
性状：
Off-White to Pink Solid
SMILES：
OCC(C12N=C(C)OC1CC1[C@@H]3C[C@H](O)C4=CC(C=C[C@]4(C)C3C(C[C@]21C)O)=O)=O
储存条件：
Amber Vial, -86°C Freezer, Under Inert Atmosphere
参考文献：
Furr, B., et al.: Pharmacol. Ther., 25, 127
A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.
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