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羟基波生坦-d6
波生坦代谢物内标物;羟基波生坦-d6
Hydroxy Bosentan-d6
  • 产品编号: CHR830273

  • CAS号: 1246817-57-1

  • 分子式:C27H23D6N5O7S

  • 分子量:573.65

英文别名:
4-[2-Hydroxy-1,1-(dimethyl-d6)ethyl]-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d6; Ro 48-5033-d6
SMILES:
OC1C2C(=CC(OCC3C=CC=CC=3)=CC=2)OC(=O)C=1
参考文献:
Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)
A labelled analogue of the active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.
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