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羟基波生坦-d4
波生坦代谢物内标物;羟基波生坦-d4
Hydroxy Bosentan-d4
  • 产品编号: CHR830272

  • CAS号: 1065472-91-4

  • 分子式:C27H25D4N5O7S

  • 分子量:571.64

英文别名:
4-(2-Hydroxy-1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy-d4)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-benzenesulfonamide; Ro 48-8634-d4; Ro 48-5033-d4
熔点:
124-127°C
可溶性:
Methanol
性状:
White Solid
SMILES:
OC1C2C(=CC=C(OCC3C=CC=CC=3)C=2)OC(=O)C=1
储存条件:
Hygroscopic, -20˚C Freezer, Under Inert Atmosphere
参考文献:
Clozel, M., et al.: J. Pharmacol. Exp. Ther., 270, 228 (1994), Gutsch, G., et al.: Cardiovasc. Drugs Ther., 10, 717 (1996), Weber, C., et al.: Clin Pharmacol. Ther., 60, 124 (1996), Krum, H., et al.: N. Engl. J. Med., 338, 784 (1998)
A labelled analogue of the active metabolite of Bosentan, a mixed endothelin receptor antagonist which is used as a vasodilator.
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