石杉碱甲
石杉碱甲；石杉碱A；(-)-石杉碱甲；(-)-石杉碱A
(-)-Huperzine A
石杉碱甲；石杉碱A；(-)-石杉碱甲；(-)-石杉碱A
(-)-Huperzine A
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产品编号： CHR826000
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CAS号： 102518-79-6
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分子式：C15H18N2O
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分子量：242.32
英文别名：
HUP, [5R-(5a,9ß-11E)]-5-Amino-11-ethylidene-5,6,9,10-tetrahydro-7-methyl-5,9-methanocycloocta[b]pyridin-2-(1H)-one, Selagine,
熔点：
223-226°C (dec.)
可溶性：
DMSO, Methanol
性状：
Off-White to Light Beige Solid
SMILES：
N[C@@](C(=O)O)(CO)CC1=CC=C(O)C=C1
储存条件：
-20°C Freezer
参考文献：
Wang, Y.-E., et al.: Acta Pharmacol. Sin., 7, 110 (1986), Ved, H.S., et al.: Neuroreport, 8, 963 (1997)
Reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. A potential therapeutic agent for Alzheimer’s disease. It reduces cell death induced by glutamate in primary cultures derived from forebrain, hippocampus, cortex and cerebellum of embryonic rat brain.
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