12-羟基-5,8,10,14-花生四烯酸
花生四烯酸代谢物；12(S)-羟基-(5Z,8Z,10E,14Z)-二十碳四烯酸；12-羟基-5,8,10,14-花生四烯酸
12(S)-Hydroxy (5Z,8Z,10E,14Z)-Eicosatetraenoic Acid
花生四烯酸代谢物；12(S)-羟基-(5Z,8Z,10E,14Z)-二十碳四烯酸；12-羟基-5,8,10,14-花生四烯酸
12(S)-Hydroxy (5Z,8Z,10E,14Z)-Eicosatetraenoic Acid
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产品编号： CHR825285
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CAS号： 54397-83-0
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分子式：C20H32O3
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分子量：320.47
英文别名：
12-HETE
SMILES：
O[C@H]1CC[C@@]2([C@H]3CC[C@@]4(C(CC[C@H]4[C@@H]3[C@@H](C=C2C1)O)=O)C)C
参考文献：
Nording, M.L. et al.: IEEE Sensors J., 10, 123 (2010); Pidgeon, G.P. et al.: Canc. Res., 62, 2721 (2002); Honn, K.V. et al.: Exp. Cell Res., 214, 120 (1994); Feldstein, A.E. et al.: J. Lipid Res., 51, 3046 (2010);
A fatty acid metabolite of arachidonic acid (A765000). Potential biomarker for asthma monitoring and diagnosis. Stimulates protein kinase C-mediated release of cathepsin B from malignant cells. Used in the study of mechanisms controlling cell cycle arrest and induction of apoptosis in prostate cancer cells via 12-lipoxygenase inhibition..
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