HU-308
HU-308
(1R,4R,5R)-rel-(+)-4-[4-(1,1-二甲基庚基)-2,6-二甲氧基苯基]-6,6-二甲基双环[3.1.1]庚-2-烯-2-甲醇
HU-308
(1R,4R,5R)-rel-(+)-4-[4-(1,1-二甲基庚基)-2,6-二甲氧基苯基]-6,6-二甲基双环[3.1.1]庚-2-烯-2-甲醇
HU-308
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产品编号: CHR673525
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CAS号: 256934-39-1
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分子式:C27H42O3
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分子量:414.62
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EINECES:202-225-1
英文别名:
(1R,4R,5R)-rel-(+)-4-[4-(1,1-Dimethylheptyl)-2,6-dimethoxyphenyl]-6,6-dimethylbicyclo[3.1.1]hept-2-ene-2-methanol
SMILES:
COC1=C(OC)C=CC(CC#N)=C1
参考文献:
Hanus, L. et al.: Proc. Nat. Acad. Sci. USA, 96, 14228 (1999); Labud, C.J. et al.: Eur. J. Pharmacol., 527, 172 (2005); Martin-Moreno, A.M. et al.: Molec. Pharmacol., 79, 964 (2011);
A specific CB2-specific agonist that inhibits forskolin-stimulated cAMP production in CB2-transfected cells. It reduces blood pressure, blocks defecation, and elicits anti-inflammatory and peripheral analgesic activity and thus may lead to new therapies for hypertension, inflammation, and pain.
Controlled Substance.
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