和厚朴酚
和厚朴酚
Honokiol
和厚朴酚
Honokiol
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产品编号： CHR669560
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CAS号： 35354-74-6
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分子式：C18H18O2
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分子量：266.33
英文别名：
3',5-Di-2-propen-1-yl-[1,1'-biphenyl]-2,4'-diol; 3',5-Di-2-propenyl-[1,1'-biphenyl]-2,4'-diol; 3',5-Diallyl-2,4'-biphenyldiol; NSC 293100;
SMILES：
CCOC1=CC=C(S(N2CCN(CC)CC2)(=O)=O)C=C1C1=NC(=O)C2N(N=C(CCC)C=2N1)C
参考文献：
Fried, L.E. et al.: Antioxid. Redox Signal,. 11, 1139 (2009); Chen, X.R. et al.: Int. J. Oral Sci., 3, 34 (2011); Shigemura, K. et al.: Cancer, 109, 1279 (2007); Bai, X. et al.: J. Biol. Chem., 278, 35501 (2003);
Honokiol is a small-molecule polyphenol isolated from the genus Magnolia. Recent studies show that Honokiol displays antiangiogenic, antiinflammatory, and antitumor properties in preclinical models, without appreciable toxicity. Honokiol has been shown to inhibit the bone metastatic growth of human prostate cancer cells.
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