高三尖杉酯碱
高三尖杉酯碱
Homoharringtonine
高三尖杉酯碱
Homoharringtonine
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产品编号： CHR596500
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CAS号： 26833-87-4
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分子式：C29H39NO9
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分子量：545.62
英文别名：
Cephalotaxine 4-Methyl (2R)-2-Hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate (Ester)
熔点：
133-135°C
可溶性：
Chloroform, Methanol
性状：
Off-White Solid
SMILES：
OCC([C@@]12OC(C)O[C@@H]1C[C@H]1[C@@H]3CCC4=CC(C=C[C@]4(C)[C@H]3[C@H](C[C@]21C)O)=O)=O
储存条件：
-20°C Freezer
参考文献：
Baaske, D., et al.: Antimicrob. Agents Chemother., 12, 298
Homoharringtonine (HHT) combined with some botanical drugs could induce cancer cells to resemble normal cells. HHT was prepared by a semi-synthetic method from Cephalotaxine, a major alkaloid of Cepahlotaxus species through the formation of α-ketoester harringtonine.
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