GW-501516
PPARδ激动剂
GW-1516
PPARδ激动剂
GW-1516
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产品编号： CGR931500
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CAS号： 317318-70-0
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分子式：C21H18F3NO3S2
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分子量：453.5
英文别名：
GW-501516；2-[2-Methyl-4-[[[4-methyl-2-[4-(trifluoromethyl)phenyl]-5-thiazolyl]methyl]thio]phenoxy]acetic Acid
熔点：
134-136°C
可溶性：
DMSO, Methanol
性状：
Off-White to Pale Yellow Solid
SMILES：
O=C1CC[C@@]2([C@H]3CC[C@@]4(/C(/C(C[C@H]4[C@@H]3CCC2=C1)=O)=C/C)C)C.O=C1CC[C@@]2([C@H]3CC[C@@]4(/C(/C(C[C@H]4[C@@H]3CCC2=C1)=O)=C\C)C)C
储存条件：
Refrigerator
参考文献：
Oliver, W.R., et al.: Proc. Natl. Acad. Sci., USA, 98, 5306 (2001), Sznaidman, M.L., et al.: Bioorg. Med. Chem. Lett., 13, 1517 (2003), Wang, Y.X., et al.: Cell, 113, 159 (2003),
An experimental drug meant to control lipids and increase the level of HDL, or good cholesterol, in the bloodstream.
A cell-permeable, thiazolyl compound that acts as a potent, high affinity, PPARδ agonist. Exhibits selectivity for PPARδ compared to PPARα
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