GW-1100
GPR40拮抗剂
GW-1100
GPR40拮抗剂
GW-1100
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产品编号： CGR930200
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CAS号： 306974-70-9
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分子式：C27H25FN4O4S
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分子量：520.58
英文别名：
4-[5-[(2-Ethoxy-5-pyrimidinyl)methyl]-2-[[(4-fluorophenyl)methyl]thio]-4-oxo-1(4H)-pyrimidinyl]benzoic Acid Ethyl Ester
参考文献：
Briscoe, C. et al.: Br. J. Pharmacol., 148, 619 (2006); Stoddart, L.A. et al.: Mol. Pharmacol., 71, 994 (2007);
GW 1100 is a selective G protein-coupled receptor GPR40 antagonist. GW 1100 has been shown to reverse the effects GPR40 agonists which induce glucose-stimulated insulin secretion.
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