GSK-360A
HIF-PHD抑制剂
GSK-360A
HIF-PHD抑制剂
GSK-360A
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产品编号： CGR797600
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CAS号： 931399-19-8
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分子式：C17H17FN2O5
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分子量：348.33
英文别名：
N-[[1-(2-Cyclopropylethyl)-6-fluoro-1,2-dihydro-4-hydroxy-2-oxo-3-quinolinyl]carbonyl]glycine
熔点：
195-197°C
可溶性：
Methanol
性状：
Beige Solid
SMILES：
CC1C=C(C)C(N2CCN(C3C(C)=CC(C)=CC=3C)C2=[Ru](=CC2C=CC=CC=2)(Cl)Cl)=C(C)C=1.C1CCC(P(C2CCCCC2)C2CCCCC2)CC1
储存条件：
Refrigerator
参考文献：
Bao, W.-K. et al.: J. Cardio. Pharmacol., 56, 147 (2010);
GSK360A orally active HIF-PHD inhibitor. GSK360A exerts systemic and local effects by stabilizing HIF-1α signaling and improves long-term ventricular function, remodeling, and vascularity in a model of established ventricular dysfunction. These findings s
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