10-甲酰-7,8-二氢叶酸
10-甲酰-7,8-二氢叶酸
10-Formyl-7,8-dihydro Folic Acid
10-甲酰-7,8-二氢叶酸
10-Formyl-7,8-dihydro Folic Acid
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产品编号： CFR700455
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CAS号： 28459-40-7
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分子式：C20H21N7O7
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分子量：471.42
英文别名：
10-FDHFA
SMILES：
C(C1C=CC(C2=CC=CC=C2C(O)=O)=CC=1)=O
参考文献：
Barford, P.A., et al.: Br. J. Cancer, 1978, 38, 122 (1978); Baggott, J.E., et al.: Biochemistry, 1979, 18, 1036 (1979); Hahm, S., et al.: Biochemistry, 33, 1473 (1994),
10-Formyl-7,8-dihydrofolic acid is a novel folate found in methotrexate-treated cells. 10-Formyldihydrofolate (H2folate) has not been found as a component of intracellular folates in normal tissues but has been identified in the cytosol of methotrexate (MTX)-treated MCF-7 breast cancer cells and normal human myeloid precursor cells.
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