FIIN-1
FGFR不可逆抑制剂1；成纤维生长因子受体不可逆抑制剂1
FIIN-1
FGFR不可逆抑制剂1；成纤维生长因子受体不可逆抑制剂1
FIIN-1
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产品编号： CFR336500
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CAS号： 1256152-35-8
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分子式：C32H39Cl2N7O4
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分子量：656.6
英文别名：
N-[3-[[3-(2,6-Dichloro-3,5-dimethoxyphenyl)-7-[[4-(diethylamino)butyl]amino]-3,4-dihydro-2-oxopyrimido[4,5-d]pyrimidin-1(2H)-yl]methyl]phenyl]-2-propenamide
参考文献：
Zhou, W. et al.: Chem. Biol., 17, 285 (2010);
FIIN-1 is a fibroblast growth factor receptor (FGFR) Irreversible Inhibitor 1.The fibroblast growth factor receptor tyrosine kinases are promising therapeutic targets in a number of cancers and FIIN-1 is a useful probe of FGFR-dependent cellular phenomena and may assist in the development of therapeutically relevant irreversible inhibitors, particularly for wild-type and drug-resistant forms of FGFR kinases.
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