宽缨酮
东革阿里提取物；巴沙克布明A；宽缨酮
Eurycomanone
东革阿里提取物；巴沙克布明A；宽缨酮
Eurycomanone
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产品编号： CER939010
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CAS号： 84633-29-4
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分子式：C20H24O9
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分子量：408.4
英文别名：
1,20-Epoxy-1,11,12,14,15-pentahydroxy-(1β,11β,12α,15β)-Picrasa-3,13(21)-diene-2,16-dione; NSC 339187; Pasakbumin A
SMILES：
N#CC1=CC=C(NC2=NC(OC3=C(C([2H])([2H])[2H])C([2H])=C(C#N)C([2H])=C3C([2H])([2H])[2H])=C(Br)C(N)=N2)C=C1
参考文献：
Wong, P.F., et al.: Phytomed., 19, 138 (2012); Nurkhasanah, M., et al., Medunion Press., 4, 109 (2008); Zakaria, Y., et al.: Cancer Cell Intern., 9, (2009);
Eurycomanone is known as a cytotoxic compound found in Eurycoma Longifolia Jack. Previous studies had noted its cytotoxic effects against various cancer cell lines. More recent research demonstrated the ability of Eurycomanone to suppress the expression of lung cancer cell tumor markers, prohibitin, annexin 1 and endoplasmic reticulum protein 28. Eurycomanone was shown to also exerts the ability to induce apoptosis through the up-regulation of p53 in human cervical carcinoma cells.
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