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溴化乙啶-d1
溴化乙啶-d1;溴乙菲啶-d1;菲啶溴红-d1
Ethidium-d1 Bromide
  • 产品编号: CER890703

  • 相关CAS号:1239-45-8(未标记)

  • 分子式:C21H19DbrN3

  • 分子量:395.31

英文别名:
3,8-Diamino-5-(ethyl-d1)-6-phenylphenanthridinium Bromide; 2,7-Diamino-10- (ethyl-d1)-9-phenylphenanthridinium Bromide; 2,7-Diamino-9-phenyl-10-(ethyl-d1) phenanthridinium Bromide; 2,7-Diamino-9-phenylphenanthridine-d1 Ethobromide; Dromilac-d1; Homidium-d
SMILES:
C(C1C=C(CCN2CCC(C(C3C=CC=CC=3)(C3C=CC=CC=3)C(N)=O)C2)C=CC=1O)=C
参考文献:
Waring, M.J., et al.: J. Mol. Biol., 13, 269 (1965), Probst, G.S., et al.: Environ. Mutagen., 3, 11 (1981),
Labelled Ethidium bromide (EtBr) (E890700). It is the most commonly used nucleic acid stain for PAGE or agarose gel electrophoresis. The fluorescence of EtBr increases 21-fold upon binding to double-stranded RNA and 25-fold on binding double-stranded DNA so that destaining the background is not necessary with a low stain concentration (10 μg/ml). Ethidium bromide has been used in a number of fluorimetric assays for nucleic acids. It has been shown to bind to single-stranded DNA (although not as strongly) and triple-stranded DNA. Because of its ability to bind to DNA, EtBr is an inhibitor of DNA polymerase. Antiprotozoal (Trypanosoma).
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