依普利酮
依普利酮
依普利酮
Eplerenone
依普利酮
Eplerenone
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产品编号: CER588775
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CAS号: 107724-20-9
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分子式:C24H30O6
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分子量:414.49
英文别名:
(7α,11α,17α)-9,11-Epoxy-17-hydroxy-3-oxopregn-4-ene-7,21-dicarboxylic Acid; γ-Lactone 7-Methyl Ester; CGP 30083; Epoxymexrenone; Inspra; SC-66110
熔点:
241-243°C
沸点:
N/A
可溶性:
Chloroform, Ethyl Acetate
性状:
White Solid
储存条件:
-20°C Freezer
参考文献:
de Gasparo, M., et al.: J. Pharmacol. Exp. Ther., 240, 650 (1987), Delyani, J.A., et al.: Cardiovasc. Drug Rev., 19, 185 (2001), Burgess, E., et al.: Expert. Opin. Pharmacother., 5, 2573 (2004), Ravis, W.R., et al.: J. Clin. Pharmacol., 45, 810 (2005),
Selective aldosterone receptor antagonist (SARA), structurally similar to Spiranolactone. Eplerenone is used alone or in combination with other medications to treat high blood pressure. Eplerenone is in a class of medications called mineralocorticoid receptor antagonists. It works by blocking the action of aldosterone, a natural substance in the body that raises blood pressure.
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