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3-去甲基甲氧苄啶
甲氧苄啶代谢物;3-去甲基甲氧苄啶
3-Desmethyl Trimethoprim
  • 产品编号: CDR295705

  • CAS号: 27653-69-6

  • 分子式:C13H16N4O3

  • 分子量:276.29

英文别名:
5-[(2,4-Diamino-5-pyrimidinyl)methyl]-2,3-dimethoxy-phenol; α-(2,4-Diamino-5-pyrimidinyl)-5,6-dimethoxy-m-cresol; 2,4-Diamino-5-(3-hydroxy-4,5-dimethoxybenzyl)pyrimidine; 3-Demethyltrimethoprim; 3’-Hydroxytrimethoprim
熔点:
>213°C (dec.)
可溶性:
DMSO, Methanol (Sparingly)
性状:
灰白色至米色固体
SMILES:
CNC[C@H]1CCCC[C@@]1(C1C=CC=C(OC)C=1)O
储存条件:
冷藏
参考文献:
Roth, B., et al.: J. Med. Chem., 24, 933 (1981); Liu, Z., et al.: Biomed. Chromatogr., 26, 1101 (2012); Schwartz, D. E., Arzneimittel-Forsch., 20, 1867 (1970)
3-Desmethyl Trimethoprim is a metabolite of Trimethoprim (T795615); an antibacterial agent that is commonly prescribed in conjunction with Sulfametoxazole (S699086) to treat patients afflicted with urinary tract infections. 3-Desmethyl Trimethoprim gets excreted in the urine of rats, dogs, and man in the form of glucuronides.
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