5'-脱氧-5'-甲硫基腺苷-d3
维生素L2-d3；5'-脱氧-5'-(甲基硫)腺苷-d3
5'-Deoxy-5'-(methylthio)adenosine-d3
维生素L2-d3；5'-脱氧-5'-(甲基硫)腺苷-d3
5'-Deoxy-5'-(methylthio)adenosine-d3
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产品编号： CDR242602
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相关CAS号：2457-80-9（未标记）
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分子式：C11H12D3N5O3S
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分子量：300.35
英文别名：
5’-S-(Methyl-d3)-5’-thioadenosine; 5’-(Methylthio-d3)-5’-deoxyadenosine; 5’-(Methylthio-d3)adenosine; 5’-Deoxy(methylthio-d3)adenosine; 5’-S-(Methyl-d3)-5’-thioadenosine; 5’-S-(Methyl-d3)thioadenosine; NSC 335422-d3; Vitamin L2-d3; 1-(6-Amino-9H-purin-9-y
熔点：
>199ºC (dec.)
可溶性：
DMSO (Slightly), Methanol (Slightly, Heated)
性状：
白色至灰白色固体
储存条件：
-20°C
参考文献：
Pegg, A., et al.: Biochem. J., 115, 241 (1969), Olopade, O., et al.: Cancer Res., 53, 2410 (1993), Hartmann, S., et al.: Clin. Chem., 52, 1127 (2006), Penner, N., et al.: J. Pharm. Biomed. Anal., 52, 534 (2010),
Labelled 5'-Deoxy-5'-(methylthio)adenosine (D242600). 5′-Deoxy-5′-(methylthio)adenosine (Methylthioadenosine) may be used as a substrate to study the specificity and kinetics of 5′-methylthioadenosinephosphorylase (MTAP) (EC2.4.2.28), a tumor suppressor gene expressed enzyme that supports the S-adenosylmethionine (AdoMet) and methionine salvage pathways. Methylthioadenosine is used in studies on bacterial quorum sensing pathways that envolve enzymes such as 5′-Methylthioadenosine/S-adenosylhomocysteine nucleosidase (MTAN).
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