去(甲基哌嗪基)伊马替尼二聚体哌嗪氯化物
伊马替尼杂质；去(甲基哌嗪基)伊马替尼二聚体哌嗪氯化物
Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride
伊马替尼杂质；去(甲基哌嗪基)伊马替尼二聚体哌嗪氯化物
Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride
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产品编号： CDR231455
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分子式：C53H51ClN12O2
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分子量：923.5
英文别名：
1-Methyl-1,4-bis(4-((4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)carbamoyl)benzyl)piperazin-1-ium Chloride
熔点：
>187°C (dec.)
可溶性：
DMSO (slightly), Methanol (slightly)
性状：
淡黄色固体
储存条件：
冷藏
参考文献：
Schindler, T., et al.: Science, 289, 1938 (2000); Drucker, B.J., et al.: N. Engl. J. Med., 344, 1031 (2001)
Des(methylpiperazinyl) Imatinib Dimer Piperazinium Chloride is an impurity of Imatinib Mesylate (G407000), a tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL).
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