登布茶碱
登布茶碱；旦布菲林
Denbufylline
登布茶碱；旦布菲林
Denbufylline
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产品编号： CDR231400
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CAS号： 57076-71-8
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分子式：C16H24N4O3
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分子量：320.39
英文别名：
1,3-Di-n-butyl-7-[2’-oxopropyl)xanthine; BRL 30892; 1,3-Dibutyl-3,7-dihydro-7-(2-oxopropyl)-1H-purine-2,6-dione;
熔点：
98-100°C
可溶性：
DMSO, Methanol
性状：
灰白色至浅米色固体
储存条件：
冷藏
参考文献：
Nicholson, C.D., et al.: Br. J. Pharmacol., 97, 889 (1989), Cortijo, J., et al.: Br. J. Pharmacol., 108, 562 (1993), Sanae, F., et al.: J. Pharmacol. Exp. Ther., 277, 54 (1996), Kumari, M., et al.: Br. J. Pharmacol., 121, 459 (1997),
A cell permeable xanthine derivatvie that acts as a selective inhibitor of phosphodiesterase IV (PDE IV). Possesses bronchodilatory properties. Displays negative inotropic effect by acting on a verapamil-sensitive site of the calcium channel in guinea pig ventricle apaillary muscle independently of its PDE inhibitory activity.
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