20,21-脱氢螺内酯
20,21-脱氢螺内酯
螺内酯杂质;20,21-脱氢螺内酯
20,21-Dehydro Spironolactone
螺内酯杂质;20,21-脱氢螺内酯
20,21-Dehydro Spironolactone
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产品编号: CDR229405
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CAS号: 132458-33-4
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分子式:C24H30O4S
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分子量:414.56
英文别名:
(7α,17α)-7-(Acetylthio)-17-hydroxy-3-oxo-pregna-4,20-diene-21-carboxylic Acid γ-Lactone; spiro[17H-cyclopenta[a]phenanthrene-17,2’(5’H)-furan] Pregna-4,20-diene-21-carboxylic Acid Deriv.
熔点:
205-208°C
可溶性:
Chloroform (Slightly), Methanol (Slightly)
性状:
白色固体
SMILES:
BrCC1=CC=C(C2N(C3=CC=C(S(N)(=O)=O)C=C3)N=C(C(F)(F)F)C=2)C=C1
储存条件:
-20°C
参考文献:
Sutter, J.L., et al.: Anal. Profiles Drug Subs., 4, 431 (1975),
20,21-Dehydro Spironolactone is an impurity of Spironolactone (S683000), a synthetic 17-lactone steroid which is a renal competitive aldosterone antagonist in a class of pharmaceuticals called potassium-sparing diuretics, used primarily to treat ascites in patients with liver disease, low-renin hypertension, hypokalemia, and Conn’s syndrome.
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