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6-脱氢皮质醇
6-脱氢皮质醇;Δ6-氢化可的松
6-Dehydrocortisol
  • 产品编号: CDR229145

  • CAS号: 600-99-7

  • 分子式:C21H28O5

  • 分子量:360.44

英文别名:
NSC 12881; Δ6-Cortisol; Δ6-Hydrocortisone; (11β)-11,17,21-Trihydroxy-Pregna-4,6-diene-3,20-dione
熔点:
227-235°C
可溶性:
Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
性状:
淡黄色固体
SMILES:
COC1=CC=C(C2C(COC3=CC4OCOC=4C=C3)CNCC2)C=C1.Cl
储存条件:
冷藏
参考文献:
Grenot, C., et al.: Biochem., 33, 8969 (1994); Justice, J.B., et al.: J. Med. Chem., 21, 465 (1978); Vigore, L., et al.: Cancer Ther., 6, 699 (2008), Puurunen, J., et al.: J. Clin. Endocrinol. Metab., 94, 1973 (2009), Lemos, D., et al.: J. Endocrinol., 201, 275 (2009), Chen, S., et al.: Am. J. Physiol., 296 (2009),
6-Dehydrocortisol is a metabolite of Cortisol (H714615), a glucocorticoid, produced by the zona fasciculata of the adrenal gland. 6-Dehydrocortisol was used in the identification of Trp-371 as the main site of specific photoaffinity labeling of corticosteroid binding globulin.
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