曲美替尼
EGFR激酶抑制剂；曲美替尼
Trametinib
EGFR激酶抑制剂；曲美替尼
Trametinib
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产品编号： CCR988930
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CAS号： 871700-17-3
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分子式：C24H20FIn4O4
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分子量：574.34
英文别名：
G 02442104; GSK 1120212; JTP 74057; N-[3-[3-Cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)-6,8-dimethy-2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl]acetamide; Trametinib; N-[3-[3-Cyclopropyl-5-[(2-fluoro-4-iodophenyl)amino]-3,4,6,7-tetrahydro-6,8-dimethyl-2,4,7-trioxopyrido[4,3-d]pyrimidin-1(2H)-yl]phenyl]acetamide;
熔点：
299-301°C
可溶性：
DMSO (Sparingly)
性状：
灰白色固体
SMILES：
C/C=C/C[C@H]([C@H](C1C(=O)N[C@@H](C(C)C)C(=O)N(C)CC(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@H](C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](CC(C)C)C(=O)N(C)[C@@H](C(C)C)C(=O)N1C)O)C
储存条件：
冷藏
参考文献：
Used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor.
Used in the systematic treatment of advanced cutaneous melanoma. An EGFR kinase inhibitor.
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