环孢素H
环孢菌素H；环孢素H
Cyclosporin H
环孢菌素H；环孢素H
Cyclosporin H
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产品编号： CCR988920
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CAS号： 83602-39-5
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分子式：C62H111N11O12
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分子量：1202.63
英文别名：
5-(N-Methyl-D-valine)cyclosporin A; Cyclo[L-alanyl-D-alanyl-N-methyl-L- leucyl-N-methyl-L-leucyl-N-methyl-D-valyl-(3R,4R,6E)-6,7-didehydro-3-hydroxy-N,4-dimethyl-L-2-aminooctanoyl-L-2-aminobutanoyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucyl]; Cyclosporine H; Sandoz 37-839;
熔点：
148-151°C
可溶性：
Chloroform (Slightly), Methanol (Slightly)
性状：
白色至灰白色固体
SMILES：
C1(C(O)C(C)C/C=C/C)C(=O)NC(C(O)C)C(=O)N(C)CC(=O)N(C)C(CC(C)C)C(=O)NC(C(C)C)C(=O)N(C)C(CC(C)C)C(=O)NC(C)C(=O)NC(C)C(=O)N(C)C(CC(C)C)C(=O)N(C)C(CC(C)C)C(=O)N(C)C(C(C)C)C(=O)N1C
储存条件：
-20°C
参考文献：
van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),
Cyclosporin is an immunosuppressant that has revolutionized organ transplantation through its use in the prevention of graft rejection. A group of nonpolar cyclic oligopeptides with immunosupppressant activity.
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