8-环戊基-1,3-二丙基黄嘌呤
8-环戊基-1,3-二丙基黄嘌呤
8-Cyclopentyl-1,3-dipropylxanthine
8-环戊基-1,3-二丙基黄嘌呤
8-Cyclopentyl-1,3-dipropylxanthine
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产品编号： CCR988500
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CAS号： 102146-07-6
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分子式：C16H24N4O2
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分子量：304.39
英文别名：
8-Cyclopentyl-3,9-dihydro-1,3-dipropyl-1H-purine-2,6-dione; DPCPX, PD 116,948
熔点：
194-197°C
可溶性：
Chloroform (Slightly), Ethyl Acetate (Slightly, Sonicated)
性状：
白色至灰白色固体
SMILES：
CN1C(=O)N(C)C2N=C(NC=2C1=O)C1CCCC1
储存条件：
-20°C
参考文献：
Gessi, S., et al.: Mol. Pharmacol., 67, 2137 (2005), Minor, T.R., et al.: Behav. Neurosci., 122, 1236 (2008), Gracia, E., et al.: J. Neurochem., 107, 161 (2008), Gessi, S., et al.: Biochem. Pharmacol., 75, 562 (2008),
DPCPX is a potent and very selective A1-adenosine receptor antagonist, with a Ki of 0.46 nM for A1 receptors in rat whole-brain membranes. Its 740-fold A1-selectivity is the highest reported for an adenosine antagonist.
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